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DIOP (2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane) is an organophosphorus compound that is used as a chiral ligand in asymmetric catalysis. It is a white solid that is soluble in organic solvents. DIOP is prepared from the acetonide of d,l-tartaric acid, which is reduced prior to attachment of the PPh2 substituents.

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